Postdoc Development and Clinical Implementation Quantitative MRI of Skeletal Muscle

Postdoc Development and Clinical Implementation Quantitative MRI of Skeletal Muscle

  • Full Time
  • Leiden

Website mri_lumc Leiden University Medical Center

Quantitative MRI of skeletal muscle is used extensively in the research realm, but clinical translation of these techniques is lacking. In this project, you will establish a clinical work-flow for quantitative MRI techniques such as water-fat mapping and T2 relaxometry on our clinical scanners, in collaboration with two other university medical centers in the Netherlands. In addition, you will develop a novel dynamic imaging protocol using phase-contrast MRI, initially in healthy volunteers and ultimately in patients. For the clinical protocol, you will collaborate extensively with clinical Radiologists, MR technicians and Neurologists to establish a clinical scanning protocol, including post-processing and reporting. For the dynamic scanning development, you will collaborate with the university medical centers in Amsterdam to implement 3D MRI PC-MRI scans in skeletal muscle using an in-magnet ergometer, and develop a software tool to analyze these data and integrate them with muscle architecture scans. You will perform small proof-of-concept studies to test this sequence in patients with neuromuscular disease.

We are looking for a passionate post-doctoral MRI researcher holding a PhD, with a background in a relevant discipline like technical medicine, (medical) physics, biomedical engineering or technology, or clinical technology. You should have experience in MRI and be interested in muscle diseases in children and young adults. Experience in skeletal muscle MRI and/or quantitative MRI is preferred but not essential. Excellent communication skills and enthusiasm for multidisciplinary collaboration are required. You should be able to work independently and have experience in programming, pulse-sequence programming and in developing post-processing tools for MRI. You are social, communicative and flexible. The research team is international and a good command of English, both written and oral, is important.

We will initially offer you a 1-year contract, with outlook on a 3-4 year position.



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