PhD Position in Neuroscience @KU Leuven – From Brain to Muscles in Cerebral Palsy

PhD Position in Neuroscience @KU Leuven – From Brain to Muscles in Cerebral Palsy

Website KU Leuven

TITLE: From brain to muscles: Elucidating gait control mechanisms in cerebral palsy

OBJECTIVE: Determine the origins of altered muscle coordination during walking in cerebral palsy.

IMPORTANCE: When successful, this project will not only provide mechanistic insights in control of walking but also pave the way for improved diagnosis and treatment, ultimately improving the quality of life for children with cerebral palsy and their families.

METHODOLOGY: We will combine state-of-the-art techniques. First, we will use high-density electroencephalography (EEG) to measure brain activity during movement. By combining EEG measures with EMG measures of muscle activity, we can infer how different brain regions contribute to muscle activity. EEG and EMG signals will be collected during both clinical tests of independent joint control and spasticity, and walking. Second, we will use diffusion magnetic resonance imaging (dMRI) to assess white matter pathways in the brain (e.g., corticospinal tract) and spinal cord and use this data to infer how damage to specific pathways alters the reliance on these pathways during movement. Third, we will assess musculoskeletal deficits and infer their interactions with motor control deficits.

For more information, please send an email to jolien.gooijers@kuleuven.be.

To apply for this job please visit www.kuleuven.be.